Tuesday, February 18, 2020

Newborn Thermoregulation at birth Essay Example | Topics and Well Written Essays - 1750 words

Newborn Thermoregulation at birth - Essay Example The temperature of the baby is dependent not only on the thermoregulation of the baby, but also on the environment and the clinical condition of the baby. It is a very interesting fact that, an unattended baby loses heat very fast and the temperature can decrease by several degrees (British Columbia Reproductive Care Program Policy Manual, 2003). Nurses and midwives who attend to deliveries have a major role to play in helping newborn babies maintain temperature. They are the first people to come in contact with the little ones and they have a major responsibility to ensure that the baby is able to maintain appropriate temperature. They also need to make sure that the environment of the baby, including the towels, resuscitation equipment and the room are pre-warmed much before the baby is delivered. Attending to the needs of temperature in babies is very important because thermal disparities can lead to devastating metabolic consequences and can contribute to increased morbidity and mortality in the newborn. In this essay, thermal regulation in a newborn will be discussed. In this context, the role of a midwife in promoting the health of the newborn will also be reviewed. The capacity of the body to maintain equilibrium between production of heat and loss of heat for sustenance of temperature of the body within a normal range is known as thermoregulation. Neutral thermal environment is that environment in which the infant uses only minimal oxygen and expends minimal energy for maintenance of temperature. Thermoregulation of newborn is a much studied and important topic because; disruptions in thermal regulation can lead to hyperthermia and cold stress, both of which can lead to devastating metabolic consequences in the newborn. The normal core body temperature of the newborn is 36.5- 37.2 degree C. Severe hypothermia is when the temperature is

Monday, February 3, 2020

Good Cholesterol and Breast Cancer risk Essay Example | Topics and Well Written Essays - 1750 words

Good Cholesterol and Breast Cancer risk - Essay Example This phenomenon reduces the risk of heart diseases but at the same time HDL also stimulates migration and activates signal transduction pathways in the human breast cancer cell lines, thus acting like a catalyst in the development of breast cancer. Thus knocking down the HDL receptor, SR-BI by some pharmacological methodologies play an essential role in regulating cellular proliferation and migration, thus controlling the growth of tumor cells, and hence SR-BI can be essentially used in the treatment of breast cancer in humans. The Popular article, Good cholesterol and breast cancer risk explains about the above detailed primary research article in a crisp manner. Though HDL that is, good cholesterol is good for health and acts like a protective shield against heart disorders, it has a negative impact on breast cancer development in humans. Higher the level of HDL in blood, higher is the risk of developing breast cancer. Thus limiting the HDL receptor, SR-BI the rapid proliferation o f tumor cells were found to be greatly reduced. The popular article also interacts with Dr. Philippe Frank, head of the research team and a cancer biologist in the Department of Biochemistry and Molecular Biology at Thomas Jefferson University who stresses on the importance of inventing more specific drugs to inhibit SR- BI and the safer level of HDL to be mentioned in cancer patients. How it relates to the theme – ‘Gender, Science and Technology’ Both the articles are interlinked and have a strong correlation with the theme of ‘Gender, Science and Technology’. The main focus of both the articles is about the treatment for breast cancer. Though the exact cause for breast cancer is still a topic under research, analysing the risk factors can show who is most likely to develop the disease. Lifestyle choices, genetic disorders and medications taken for some kind of diseases may be some of the risk factors for developing the disease but some risk factors are more vulnerable, particularly one’s ‘Gender’. Breast cancer is most common in women because they have more breast tissue than men. Breast cancer causes include what stimulates the breast tissue to grow and develop. Female relatives can also be a risk factor for getting breast cancer. If one’s mother, sister or daughter have breast cancer, the chances of getting the disease is doubled. Though cancer of several types is the leading cause of death in the world, medical science and technology has empowered people to make life changing decisions by matching them with modern and advanced treatment options based on individual conditions of the patients. Modern science and technology has revolutionized the breast cancer research therapies and now chances of overcoming breast cancer are much better than in earlier days. Main Scientific Claim The authors claim that their examination about the role of HDL and SR-BI in the regulation of cellular signalling pathwa ys in breast cancer cell lines and development of tumors show that, HDL can stimulate the signal transduction pathways in the human breast cancer cell lines. Then, accelerate the formation of tumors and hence knocking down of HDL receptor, SR-BI limits the